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Highlighting this protective role, in vivo astrocyte-specific disruption of autophagy exacerbates hallmark AD pathologies, including greater plaque burden, increased tau phosphorylation, reactive astrogliosis, neuronal loss, and cognitive impairments, while astrocytic LC3B overexpression ameliorates these phenotypes [135]

SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer

In this study, the mice were pretreated with resveratrol 5 days before and 1 day after prior to a large single dose partial-body (abdominal) irradiation