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In the case of the colitis-associated cancer (CAC) mouse model, IKK genetic deletion in intestinal epithelial cells greatly reduces the incidence of tumors through the increase of apoptosis [52], while its KO in the macrophage significantly reduces tumor size by suppressing the expression of pro-inflammatory factors [53, 54]

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Latremoliere A, Woolf CJ

10.5296/emsd.v12i2.20979 [Google Scholar] Lu Y-M, Xiang W-Z, Wen Y-H (2011) Spirulina (Arthrospira) industry in Inner Mongolia of China: current status and prospects