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The alternative strategy focuses on monitoring epigenetic changes during treatment and intervening with epigenetic drugs before the stabilization of resistant epigenetic states, which may delay or prevent resistance developmentpotentially enabling cancer to be managed as a chronic condition [181]

Our proposed approach is most consistent with section 1847A(c)(5)(B) of the Act, which directs the Secretary to update quarterly a drug's ASP payment limit using manufacturer's ASP data from the most recent calendar quarter for which such data are available

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Number of worker-submitted hazard or success reports