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143,144 The mutated IDH1 and IDH2 proteins are endowed with a novel ability to catalyze the reduction of -KG to generate a rare metabolite, 2-hydroxyglutarate (2-HG), while consuming NADPH

Chapter 11 - Curcumin and molecular targets in eye diseases

(1) In addition to these, glutathione is also responsible for modulating the ability of depigmentation of cytotoxic agents that target melanocytes, thereby potentiating their effect and further aiding the process of skin lightening

For instance, one study found that growth hormone (GH) secretagogues similar to ipamorelin helped increase lean body mass and decrease fat mass in a group of seniors [11], but it is not known whether ipamorelin offers these benefits