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If not applied correctly or excessively, improper usage can lead to minor adverse effects, thus an understanding of precautions is quite important when adding it to the routine

KEAP1-NRF2 system as a potential therapeutic target in ALS The presence in ALS of increased levels of OS markers and impaired antioxidant defense in the brain and peripheral tissues [25] together with the central role of NRF2 in inducing target genes to counteract OS [272] make the KEAP1-NRF2 system a suitable therapeutic target for drugs and small molecules

Minimum Dosage is 1 lozenge a day, but you can take up to a maximum 4 lozenges a daily