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The liver is one of the hardest-working organs in the body

Prajapati V, Singh AK, Kumar A, Singh H, Pathak P, Grishina M et al

When the patients were divided into two groups such as the higher and lower groups according to the median value of GPX-3 concentration of 82.8 ng/mL, in Kaplan Meier survival analysis, however, no significant difference in cumulative patients survival rates between patients in the higher and lower groups was observed (Supplementary Figure S2)

Regarding hydrophobic bonds, the ligands were bound to the following residues of GPx4: Ile22, Val57, Ala61, Phe78, Ala94, Tyr96, Ile129, Leu130, Ala133, Trp136, Pro155, and Met156 for Ferrostatin