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While data from a RCT controls for many of the potential confounding factors, using data from non-primary endpoints requires caveats

There are so many resources outlining the signs and symptoms of DKA, including the being very thirsty urinating a lot more than usual If untreated, more severe symptoms can appear quickly: fast, deep breathing dry skin and mouth flushed face fruity-smelling breath headache muscle stiffness or aches being very tired nausea and vomiting stomach pain Without treatment, DKA leads to death

The aim is to determine when B12 will serve as meaningful metabolic support and when your energy issues point somewhere else entirely