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-lipoic acid is a trap for hydrogen peroxide and hypochlorite, and dihydrolipoic acid is for superoxide radical [6]

Numerous preclinical reports have highlighted the ability of curcumin to restore reduced GSH levels and the activities of GSH-related antioxidant enzymes in the myocardium after exposure to cardiotoxic factors, for example, DOX, I/R, diabetes, hyperthyroid conditions, and copper sulfate [184,185,186,187,188]