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In this study, we demonstrated that cystine decreased the intracellular GSH/GSSG ratio in Salmonella , which disrupted cellular redox homeostasis, increased ROS production, and activated the Fenton reaction, thereby enhancing the bactericidal effect of gentamicin on drug-resistant bacterial strains

Desondanks als we in deze studie kijken naar de voor ons relevante subgroep, de patinten boven de 150-lijn van het nomogram (n=959) dan zijn er ook geen verschillen tussen beide regimes wat betreft hepatoxiciteit (maar hiervoor was niet gepowered)