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Experimental work on intestinal anastomosis models and related gastrointestinal injury systems has evaluated endpoints including tissue tensile strength, inflammatory signaling markers, and vascularization within healing intestinal segments

J Endocrinol Invest (2019) 42:144350

Infants operated on for necrotizing enterocolitis: towards evidence-based pain guidelines

however, the response intensity is difficult to evaluate due to the differences in experimental designs, RPM sources, and purity among studies (Wei et al., 2022)