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DOI: 10.1038/s41392-022-00904-4

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

When BaP enters the human body, it undergoes a series of chemical reactions, and affects DNA methylation levels, which contributes to carcinogenesis of human respiratory system, digestive system and reproductive system, and eventually results in the occurrence of a variety of cancers (Fig