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Additional therapeutic strategies, such as the use of proton pump inhibitors (e.g., esomeprazole) to limit intestinal iron absorption, are also under clinical investigation [112]

Because these patients symptoms skull asymmetry, infantile spasms, dwarfism, brain atrophy, sensory impairments, and glycosylation abnormalities resembled type II congenital disorder of glycosylation (CDG), this study established a link between Mn deficiency and hereditary CDG, showing that mutations in SLC39A8 can decrease the supply of Mn to the Golgi enzyme -1-galactosyltransferase, which is essential for glycoprotein biosynthesis

Heavy Metal Detox Heavy metals like lead, mercury, arsenic, and cadmium can accumulate in the body through exposure to contaminated water, food, air pollution, and industrial chemicals[5]

Palma et al., 2020)