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International Journal of Particle Therapy 8(1):261-272, 2021

Main text Vitamin B6 metabolism disorders and epilepsy Vitamin B6 encompasses six compounds, namely pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), along with their respective 5-phosphates

Considering that ALA treatment reduced GSSG/GSH ratio (despite the nonsignificant increase in GR activity compared to highly upregulated GPx expression), we suggest a possibility that ALA directly assists or partially substitutes for GR function in the GSHGSSG redox reaction