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Upstream action of Ras proteins Ras proteins, such as KRAS, NRAS, and HRAS, are small GTPases that function as molecular switches in the MAPK signaling pathway

Slow release and delivery of antisense oligonucleotide drug by self-assembled peptide amphiphile nanofibers

mRNA expression of genes involved in the mevalonate pathway, including 3-hydroxy-3-methylglutaryl-CoA synthase 1 ( HMGCS1 ), 3-hydroxy-3-methylglutaryl-CoA reductase ( HMGCR ), mevalonate kinase ( MVK ), mevalonate diphosphate decarboxylase ( MVD ), and isopentenyl-diphosphate delta isomerase 1 ( IDI1 ), were upregulated upon Al-CPI stimulation alone or when comparing LPS + Al-CPI 1 M versus LPS alone ( Figure 7 )