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When systemic inflammation is already elevated by dietary factors, the local inflammatory response to a blocked pore can be amplified - breakouts become more severe, more persistent, and slower to resolve

Voclosporin, a novel calcineurin inhibitor, was investigated in a phase II trial for lupus nephritis as a combination therapy with mycophenolate mofetil (AURA trial)

After incubation with horseradish-peroxidase-conjugated secondary antibodies, signals were detected by Western Lightning Plus enhanced chemiluminescence Substrate (PerkinElmer, NEL103E001EA)