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Tramullas et al., 2007

This is achieved by GSH reductase, which uses NADPH to regenerate GSH from GSSG, linking antioxidant capacity directly to cellular metabolic status

Injection solution was prepared as follows: 20 ng/l gRNA-IR was incubated with 20 ng/l Cas9 protein for 15 minutes at room temperature to generate the ribonucleotide complex RNP