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Such a multi-electrode arrangement was, for example, used to demonstrate the ability of the cerebellar cortical parallel fiber system to transform sequential inputs to the granule cell layer into synchronous inputs to postsynaptic Purkinje cells [312, 331]

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& Bellander, B.-M

However, most of the natural products targeting HDAC and/or DNMT lack isoform selectivity, which is important for determining their potential use as therapeutic agents