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Nano-sensitizers acquired many advantages for radiation dose accumulation and radiation effects enhancement, thereby improving the efficacy of radiotherapy, also increase tumor sensitivity to radiation through reactive oxygen species (ROS) [19]

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Treatment with 5-Amino-1MQ combined with diet transition produced dramatic whole-body adiposity and weight loss, rapidly normalising these measures to levels comparable to age-matched lean control animals an outcome that diet switch alone was unable to achieve in the same time frame