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More in detail, we used the quadratic multiomic metabolic transformation algorithm (qM 2 TA) to impute the metabolic transformation underlying exposure to each drug and their combination by finding the intracellular metabolic flux rewiring most consistent with the transcriptomics and metabolomics measures (Fig

While extensive research has elucidated many epigenetic alterations associated with cancer, the exact mechanisms by which these changes influence disease progression remain incompletely understood

While effective, the complexity and high cost of synthesizing these DNA-based probes present a barrier to scalability [146]

Renaud JB, Walsh JP, Sumarah MW (2022a) Optimization of aflatoxin B1-lysine analysis for public health exposure studies