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Springer, New York, pp 10291050 Dringen R, Bishop GM, Koeppe M, Dang TN, Robinson SR (2007) The pivotal role of astrocytes in the metabolism of iron in the brain

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Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K (2004) Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

The lack of IPA not only damages the local immune defense of the intestine but also inhibits its ability to cross the blood-brain barrier, leading to insufficient activation of AHR in the central nervous system and thereby affecting the anti-inflammatory response of astrocytes