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doi:10.1001/jamaoto.2021.4470

Neuropathy risks post surgery primarily stem from nutritional deficiencies, notably vitamin B 1 , B 6 , and B 12 , with 4.6% to 16% of patients experiencing neurological symptoms [42]

In fact, the benefits of B12 all boil down to two biochemical reactions: The conversion of methylmalonyl-coenzyme A to succinylcholine coenzyme A (by methylmalonyl-CoA mutase, with adenosylcobalamin as a cofactor), and the remethylation of homocysteine to methionine (with methylcobalamin being a cofactor for methionine synthase)