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Five fields per mouse were randomly selected for analysis, and Fiji ImageJ was used for image quantification

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While drugs targeting ferroptosis hold promise, they also present challenges: (I) lack of specificity: where iron chelators may disrupt normal cellular iron metabolism and cause iron-deficiency anemia

For example, in a 2021 study, as little as 100mg of dihydroberberine increased berberine blood levels better than 500mg of HCl, and another 2021 study (by Indena, the company that makes Berbevis) found that a phytosomal preparation resulted in a tenfold improvement in bioavailability compared with HCl.48 51 Based on these studies, you might conclude that the two bioenhanced forms are superior to berberine HCl