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Phytomedicine 83 , 153471 (2021)

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In mitochondria, electron transfer potentials are coupled to the genesis of transmembrane protonic forces, a form of Gibbs free energy that can be readily utilized for the synthesis of ATP

GSH also detoxifies electrophilic xenobiotics compounds (chemical carcinogens, environmental pollutants, drugs, etc.) and their metabolites to GSH adduct (GS-X) in the direct catalysis of glutathione-S-transferase (GST, primary approach) [32]