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5.2 Metabolic dysfunction-associated steatotic liver disease MASLD has emerged as a prominent global health challenge due to its asymptomatic manifestations, high prevalence and potential intra and extrahepatic consequences, often concurrent with the prevalence of obesity and T2DM and is a major cause of liver-related morbidity and mortality (Anonymous, 2025)

doi:10.1007/s00726-016-2340-y Stefanello FM, Kreutz F, Scherer EBS, Breier AC, Vianna LP, Trindade VMT, Wyse ATS (2007) Reduction of gangliosides, phospholipids and cholesterol content in cerebral cortex of rats caused by chronic hypermethioninemia

Injection sites can be local (near injury) or systemic (abdominal or thigh)