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Through these mechanisms, IGF-1 LR3 stimulates cellular anabolism, enhances glucose and amino acid uptake, increases protein synthesis, and inhibits protein degradation

However, after continued daily administration of sermorelin, its negative effects on brain and pituitary GHRH receptors reduces the amount of hGH and IGF-1 that results from the same dose of analog that previously produced a robust effect (Figure 7)

GHK-Cu is used as an ingredient in topical cosmetics, but its injectable form is not approved by the Food and Drug Administration (FDA), raising the risk of immune reactions

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