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Next, we investigated the effect of long-term low v-ATPase deficiency on cytosolic pH, given that alterations in cytosolic pH homeostasis can have significant consequences for mitochondrial functionand vice versa

5 Anticancer effects of PYC Anticancer drugs remain essential in cancer treatment because they directly or indirectly induce DNA damage, leading to cellular senescence or apoptosis through the inhibition of cancer cell proliferation ( in vitro and in vivo models, supporting its role as a natural chemopreventive and therapeutic agent

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