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Mycobacterium Abscessus Cording Prevents Phagocytosis and Promotes Abscess Formation

Partially protected peptide 4a was dissolved in 2,2,2-trifluoroethanol and hydrogenated in the presence of palladium on charcoal (10%) with hydrogen gas at 30C

Abbreviations 3HSD: 3-Hydroxysteroid dehydrogenase AI: Aromatase inhibitors BC: Breast cancer CDK2: Cyclin-dependent kinase 2 DALYs: Disability-adjusted life year EGCG: Epigallocatechin gallate ER: Estrogen receptors HaCaT: Cultured human keratinocyte HepG2: Hepatoma G2 HER2: Human epidermal growth factor receptor 2 MCF-7: Michigan cancer foundation-7 MDO: Modularly designed organocatalysts MTT: (3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) NSCLC: Non-small cell lung cancer PR: Progesterone receptor SAR: Structure activity relationship SERMs: Selective estrogen receptor modulators References World Health Organization

As expected, exposure to RSL3 promoted cell death in young T cells and was rescued by ferrostatin-1 or liproxstatin-1, two commercially available inhibitors of ferroptosis (Extended Data Fig