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Despite its low sensitivity, this screening test is widely used (4,5) in detecting PC when a 4 ng/ml cut-off point is used

Levey AS, Coresh J, Greene T, Stevens LA, Zhang Y, Hendriksen S et al (2006) Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate

The significant parameters controlling GT productivity by the potent fungus were optimized by the face-centered central composite design (FCCD), to assess the variables mutual interactions, as represented by 5 levels low 1, medium 0, and high + 1, with center point repeated 6 times