dihexa analog of angiotensin iv (human) Dihexa (also known as PNB-0408)
Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive Antidementia Agents PMC A Role for the Brain RAS in Alzheimer's and Parkinson's Diseases PMC PDF) The Procognitive and Synaptogenic Effects of Angiotensin IV Derived Peptides Are Dependent on Activation of the Hepatocyte Growth Factor c Met System
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