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[DOI] [PubMed] [Google Scholar] 563.Holm L, Cassidy JD, Carroll LJ, Borg J

Activated Rheb subsequently activates mTORC1 (87), promoting mRNA translation by releasing the inhibition on eIF4E (88) and stimulating protein synthesis via the phosphorylation of ribosomal protein S6 (89)

Circulation 2004;109:2191-2196

The ANLS hypothesis draws heavily on data from techniques that measure metabolites and oxygen directly in the brain parenchyma (e.g., microsensors, microdialysis), emphasizing the rapid dynamics of a local lactate and oxygen pool (Hu and Wilson, 1997