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Our experience shows this is an unnecessary risk and waste for most research applications

Deficient AMPK activity contributes to hyperexcitability in peripheral nociceptive sensory neurons and thermal hyperalgesia in lupus mice

[PubMed]101

This enables the killing of not only the primary target cells highly expressing the target antigen but also neighboring cells with low or negative antigen expression via the "bystander effect," effectively overcoming tumor heterogeneity