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Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a

This is because HGF has the ability to blunt inflammation in adipose tissue, by increasing M2 macrophage polarization, and consequently augmenting the expression of IL-10, both of which are positively associated with insulin sensitivity (see Figure 4)