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These findings could enhance our understanding and therapeutic targeting of the metabolic role of the PNPLA3 in immunometabolism

326 Elevated free fatty acids in the cerebrospinal fluid of AD patients can be neurotoxic, causing mitochondrial uncoupling and bioenergetic dysfunction

51,53 Collectively, these findings suggest that both canonical and noncanonical NF-B pathways are involved in the generation and effector functions of inflammatory T cells, although they differ in mechanisms of activation and function

Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study