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Mutat Res;(Netherlands)

Together, these intriguing findings demonstrate that RSL3 can effectively induce DNA damage, impair DNA damage repair response, and trigger autophagy in thyroid cancer cells by inhibiting GPX4

[19] This conversion is catalyzed by glutathione reductase: NADPH + GSSG + H 2 O 2 GSH + NADP + + OH Roles [edit] Antioxidant [edit] GSH protects cells by quenching (reducing) reactive oxygen species