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Ferroptosis is a lysosomal cell death process

Direct inhibition of factor VII activity by acetaminophen (minor prolongations resulting in a PT that usually is 10,000 mg/L x IU/L is strongly associated with hepatotoxicity *

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For lipoxygenase (LOX) activity, supernatant (100 L) was combined with a mixture (2.9 mL) containing sodium linoleate solution (10 mmol) and phosphate buffer at pH 7.0 (50 mmol) followed by the absorbance measurement at 234 nm (Chen et al