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Notably, phosphorothioates and dithioates are often pro-toxicants, requiring oxidative desulfuration by hepatic cytochrome P450 enzymes to convert into active oxon forms (e.g., parathion paraoxon), which are potent acetylcholinesterase inhibitors

TBI induced the change of gut microbiota components, including a decrease of Anaerotruncus , Firmicutes-unclassified, Lachnospiraceae-unclassified , and Ruminococcus-1 and increase of Muribaculum and Gastranaerophilales-unclassified ( Figure 4B )

This underscores the urgent need for the routine monitoring and global harmonization of residue standards

Important: Researchers should consult product labeling and facility-specific protocols when establishing storage timelines and handling procedures