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J Pharm Pharm Sci 2016;19:38298

While higher doses aren't always necessary, it's helpful to know that there's no known risk of consuming excessive amounts of vitamin B12

Briefly, 1106 cells were incubated overnight in 100-mm dishes containing 10 ml of RPMI-1640 medium supplemented with 10% FBS without penicillin, streptomycin and neomycin