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Also, diacetyl is found in plants such as tobacco and is commonly used to flavor processed foods

Co-administration with other drugs that are metabolized by CYP 3A4 (e.g., indinavir, erythromycin) may increase their clearance, resulting in decreased plasma concentration

In hopes of combatting the growing problem, in March 2018, the Lung Association sued the FDA with several partner organizations to compel it to follow the Tobacco Control Act and complete the review of all e-cigarettes, cigars and other newly regulated tobacco products

[57] For individuals that were current smokers, e-cigarette use was associated with higher odds of planning to quit smoking