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Mol Nutr Food Res 53(Suppl 2):S219 Vermeulen M, Boerboom AM, Blankvoort BM, Aarts JM, Rietjens IM, van Bladeren PJ et al (2009) Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya

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Acetyl CoA is an important metabolite that intervenes in the Krebs cycle of the oxidative metabolic pathway carried out in the mitochondria, and in turn, a cofactor in the production of the N-acetyltransferase/serotonin (AANAT/SNAT), essential in the synthesis of melatonin [64]

Labeling cells with [U- 13 C]-pyruvate and [U- 13 C]-acetate, which serve as the precursors of the acetyl group in acetyl-CoA, produced S-acetylglutathione with isotopologue of M + 2 (Supplementary Fig