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To determine the robustness of the screen the statistical parameter, Z-prime (Z) was determined (25) and at 40 hours of growth the values obtained were very significant (for Screen I =0.95 and for Screen II = 0.91) which suggested that the screens we developed were robust and would be compliant for a high throughput setting (Figure S6)

JamaliMoghadamSiahkaliSZarezadeBKoolajiSSeyedAlinaghiSZendehdelATabarestaniMet al

Large population studies show that adults with lower carotenoid consumption tend to report shorter sleep duration, suggesting that antioxidant status may influence healthy sleep patterns.34 A smaller randomized trial tested 12mg of astaxanthin daily for eight weeks and found improvements in several sleep parameters, along with reduced perceived stress compared to placebo.4 The authors proposed that astaxanthins antioxidant and neuroprotective activity including its ability to cross the bloodbrain barrier could help stabilize oxidative stress in brain regions involved in regulating sleep and mood

Polycystic ovary syndrome: (Stein-Leventhal syndrome) A syndrome of secondary oligomenorrhea and infertility, associated with multiple follicle cysts of the ovary and failure to ovulate