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Regulation of HippoYAP signaling axis by Isoalantolactone suppresses tumor progression in cholangiocarcinoma

Last reviewed: June 1, 2026 Last updated: June 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

In marine organisms and some human pathogens, this enzyme fulfills the function of a sulphoxide synthase catalyzing the first step in ovothiol A biosynthesis to generate an unmethylated sulphur-containing thiohistidine precursor of this metabolite 41,42