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Obesity is a significant risk factor affecting the onset and progression of OA

These include the constraints associated with the short half-life of [ 68 Ga] (impossible to ship to other hospitals or inject many patients in one day) and the accumulation in the kidneys, potentially causing nephrotoxicity when the radioligand would be changed for therapeutic purposes

This suggests that AOD 9604 may potentially augment the anti-cancer potency of doxorubicin while possibly minimizing unintended actions associated with non-target tissue exposure

The results showed meaningful improvements in functional outcomes compared to standard care alone