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Regulation of the pentose phosphate pathway in cancer

Histological examination showed better granulation tissue formation, improved re-epithelialization, enhanced dermal remodeling, and higher collagen deposition compared to untreated controls

Type I interferon promotes cell-to-cell spread of Listeria monocytogenes

Since SIRT1 knockdown is shown to increase the nuclear level of acetyl-p53 and abolish the protective action of 4-OH-E 1 against glutamate neurotoxicity, these findings suggest that 4-OH-E 1 exerts its protection by promoting SIRT1-mediated p53 deacetylation, which then facilitates p53 cytoplasmic translocation and thereby suppresses p53-dependent neuronal death