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Pairing glutathione with supporting nutrients like vitamin C and N-acetylcysteine can further enhance its results

2.3.2.1 Effects of PA on hepatic oxidative stress PA has potential antioxidative activity both in vitro and in vivo

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In mitochondria, electron leakage at Complexes I and III generates superoxide (O), a process often exacerbated by mutations in assembly factors like cytochrome c oxidase assembly factor 1 (COA1) or cytochrome c oxidase assembly factor 18 (COX18) [16, 17]