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Crizotinib (PF-02341066) as a potent inhibitor of c-Met and ALK received approval for the treatment of patients with locally advanced or metastatic NSCLC that is ALK-positive in 2013 [70]

Research indicates Dihexa treatment can improve functional outcomes in animal models of cognitive impairment, with behavioral improvements correlating with structural brain changes including increased synaptic density and improved neural connectivity patterns

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FY22 SBIR Program Summary Agency Dollars Obligated % Total DOD 2,145,738,302 52.134 % DOE 337,322,776 8.196 % NSF 202,553,284 4.921 % NASA 189,474,131 4.604 % USDA 34,738,810 0.844 % DHS 17,032,004 0.414 % DOC 14,398,941 0.350 % DOT 13,856,714 0.337 % ED 13,094,281 0.318 % EPA 7,290,965 0.177 % HHS 1,140,312,654 27.706 % Total $4,115,812,862 See more details at 2022 SBIR and STTR Annual Report on sbir.gov