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Diet-derived ceramides species might target and disrupt mitochondria function leading to defective energy balance and neurodegeneration

PubMed Singh A, Ye M, Bucur O, Zhu S, Santos MT, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R

Therefore, intraperitoneal administration is preferred over the oral route to avoid the potential degradation of biological agents in in vivo animal experiments (127)