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In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase Cancer Res 1993 53 : 46194626 Bridgewater JA et al

Sin embargo, tambin es capaz de participar en la conjugacin no enzimtica de algunos productos qumicos, como en el caso de la N-acetil-p-benzoquinona imina (NAPQI), el metabolito reactivo formado por la accin del sistema citocromo P450 sobre el paracetamol (o acetaminofeno, como se conoce en los Estados Unidos)

Stacking buzzy ingredients is a very common mistake I see because its expensive and rarely is it additive or synergistic, he said, noting that you should never have more than three actives which include vitamin C, AHAs, BHAs, and retinoids in a routine