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Biochemical parameters were evaluated in neonatal calves with diarrhea, and it was reported higher urea and creatinine concentrations in animals with diarrhea compared to healthy ones, probably because of dehydration ( One of the indices to determine the diagnosis of metabolic diseases in ruminants is the total activity of lactate dehydrogenase and its isoenzymes, and there is an increase in LDH activity when clinical symptoms of the disease are present ( It is already known in practice and in the literature that calves at this early stage of life are likely of having higher incidence of diseases and are also submitted to the critical stress period of weaning management

Also, lower mitochondrial DNA-encoded cytochrome c oxidase subunit 2 levels showed no association with a higher malignancy degree and lower CoQ protein levels

Disruption of the circadian clock in mice increases intestinal permeability and promotes alcohol-induced hepatic pathology and inflammation

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