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Taken together, UNC10415667 reveals that slightly larger benzaldehyde-based degraders can effectively recruit FBXO22 via C326 to promote the potent degradation of NSD2 without requiring chemical protection or bioactivation

Pallavicini, P

In essence, the gut microbiota, through its sophisticated enzymatic machinery and dynamic interplay with the host, orchestrates the BA pool, transforming BAs into a diverse array of signaling molecules