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Jain N, Thompson PA, Burger JA, Borthakur G , Bose P, Estrov Z, Ferrajoli A, Takahashi K, Garg N, Wang X, Gandhi V, Plunkett W, Kanagal-Shamanna R, Patel K, Lopez W, Kantarjian HM, O'Brien SM, Keating MJ, Wierda WG

29 Besides human hydrolases, macrodomain-containing hydrolases from VEEV and SARS can remove the ADP-ribosylation of RNA catalyzed by PARPs, suggesting a potential mechanism of pathogenesis via inhibiting the antiviral activity of IFN-stimulated genes, PARPs

Once extracted, the protein free acidic sample can be stored at -20C for several months or indefinitely at -80C

A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs